‘Abuse Deterrent’ ADHD Tx May Face Uphill Approval Path

An abuse-deterrent stimulant product for attention deficit-hyperactivity disorder (ADHD) got a skeptical review from FDA technical staff ahead of an advisory committee meeting later this week.

AR19 is an oral amphetamine sulfate immediate-release capsule formulated to reduce non-oral abuse. The drug, developed by Arbor Pharmaceuticals, will go before the Psychopharmacologic Drugs Advisory Committee (PDAC) and the Drug Safety and Risk Management (DSaRM) Advisory Committee on Thursday.

The main question looming over AR19 is whether it will indeed deter intranasal and IV abuse through its novel formulation. In briefing documents prepared for panel members, FDA staff suggested they weren’t persuaded by the company’s studies.

Non-medical use of prescription stimulants has remained relatively stable since 2010 and, in 2018, 2% of the U.S. population was misusing stimulants, according to the briefing documents. Young adults are more likely than adults of other ages to misuse stimulants, and the vast majority of misuse occurs

Read More

Study: Pot users may need more anesthesia, painkillers during, after surgery

Marijuana users appear to need more anesthesia than nonusers, and also more opioids to relieve their pain after surgery, a new, preliminary study reports.

Users of cannabis products who had surgery for a broken leg required higher doses of sevoflurane, an inhaled anesthetic that keeps you asleep during a procedure. These folks also required nearly 60% more opioid painkillers per day while recuperating in the hospital, the researchers found.

The results jibe with earlier studies indicating that marijuana users might need more anesthesia initially to put them under, said lead author Dr. Ian Holmen, a resident anesthesiologist with the University of Colorado Anschutz Medical Campus in Aurora.

“It’s similar to flying a plane. You have a takeoff section, and then you have your cruising section and then your landing. These in anesthesia are induction, maintenance and emergence,” Holmen said. “We found that it’s not just in the induction phase of

Read More

Whistleblower who alleged White House virus failures resigns

A high-ranking government whistleblower who alleges the Trump administration fumbled its coronavirus response has resigned, saying he has been forced out

Lawyers for Dr. Rick Bright said he was sidelined at the National Institutes of Health, where he had been transferred this spring after being ousted as head of a biodefense agency.

Attorneys Debra Katz and Lisa Banks said NIH superiors ignored a national coronavirus testing strategy that Bright developed because he had become politically toxic within the Trump administration.

“NIH leadership declined to support Dr. Bright’s recommendations because of political considerations, plain and simple,” the lawyers said. “This was the proverbial straw that broke the camel’s back. He can no longer countenance

Read More

Over 50 Salt Lake City officers under quarantine ahead of vice presidential debate

The city has seen a rise in new cases over the last month.

Salt Lake City’s latest rise in novel coronavirus cases has affected dozens of the city’s police officers, with at least 9% under quarantine ahead of Wednesday night’s vice presidential debate.

As of Tuesday evening, 17 officers tested positive for COVID-19, and 52 were in quarantine, Detective Michael Ruff told ABC News. On Monday, the department said 15 officers tested positive and 25 others were under quarantine.

A 2019 report by the Salt Lake City police department said the force had 542 uniformed officers, and Ruff could not say how much that number has changed over the year.

Ruff the department’s duties during the debate at the University of Utah shouldn’t be hindered because other agencies, including the university police,

Read More

California governor’s office tells diners to wear masks “in between bites”

The California governor’s office put out a tweet on Saturday advising that restaurant-goers keep their masks on while dining. “Going out to eat with members of your household this weekend?” the tweet reads. “Don’t forget to keep your mask on in between bites. Do your part to keep those around you healthy.”

In California, masks are required for anyone going outside their home, as well as workers in customer-facing businesses, offices, factories, and health care professionals, among others, according to the state’s COVID-19 guidance.

While children under 2 years old and those with breathing troubles or medical exemptions do not need to wear a mask, everyone

Read More

Michigan health department issues emergency orders restricting nursing home visits

The Michigan Department of Health and Human Services has issued orders essentially reinstating restrictions on long term care facilities and other facilities due to coronavirus.

The orders come after Gov. Whitmer’s previous Executive Order was struck down by the state Supreme Court last week, saying she drew authority from a 1945 law that is unconstitutional.

MDHHS Director Robert Gordon said this new order relies on authorities that were first enacted after the Spanish Flu of 1918, and that were not at issue in the Michigan Supreme Court’s decision.

“Ensuring the health and safety of vulnerable Michiganders and those under our care is of the utmost importance,” Gordon said. “This order reestablishes protections that have helped Michigan sharply reduce the loss of life in nursing homes. With the level of COVID in Michigan rising again, these protections are more critical than ever.”

As of Oct. 5, about 10% of COVID-19 cases

Read More

SCL Health And Community Leaders Encourage 2020 Flu Shots

In an effort to increase awareness of the importance of the annual flu shot and to encourage individuals to get vaccinated this year, Denver Mayor Michael Hancock joined forces with community members to share why they get their flu shot in a powerful video. View their testimonials here.

In addition to sharing these compelling videos, we have also partnered with SCL Health physicians and clinical leaders to develop easy-to-understand resources to help educate the general public on the importance of getting a flu shot and to share information on the similarities and differences in symptoms for the common cold, flu and COVID-19. With all we continue to learn about COVID-19 and symptoms related to the virus, we wanted to provide a resource for reference and encourage individuals to consult their physician for a professional diagnosis and appropriate treatment options. More information on why individuals should get a flu shot

Read More

Fighting COVID-19 Misinformation, Global Health Student Tweets the Truth

As spring term approached in the midst of the coronavirus pandemic, University of Oregon senior Myriah Kunipo-Aguirre found herself hunkered down at her parent’s house in Carson, California. 

She needed to complete field work for her global health minor, but the UO canceled travel and internship programs as it grappled with the spread of COVID-19.

Kristin Yarris, director of the Global Health Program, recognized the problem confronting Kunipo-Aguirre and other students. She quickly launched a course called Global Health Crisis to give students a chance to complete required field experience where they resided. 

Kunipo-Aguirre tracked the outbreak in her own backyard—Los Angeles County—using Twitter to report on the emergency response of state and county officials. With 10 million residents, Los Angeles County is the most populous county in the country, and among the first to impose lockdown measures intended to slow the spread of COVID-19. 

Kunipo-Aguirre created a Twitter feed

Read More

Clover Health SPAC plans and growth projections for Medicare

  • The Social Capital SPAC led by billionaire Chamath Palihapitiya is acquiring Clover Health in a $3.7 billion deal that’ll take the health insurance company public. 
  • In 2021, Palihapitiya projects the company will grow its membership roughly five times what it was this year.
  • Clover Health president and chief technology officer Andrew Toy said that projected growth largely comes from the potential participation in a new Medicare program that’s yet to be finalized. 
  • For more stories like this, sign up here for Business Insider’s daily healthcare newsletter.

Social Capital’s Chamath Palihapitiya is looking to acquire the health insurance company Clover Health via a SPAC. 

The special-purpose acquisition company Social Capital Hedosophia Holdings Corp. III will merge with Clover in a $3.7 billion transaction that’s slated to close in 2021, the companies said in a statement.

Clover offers private health-insurance plans for seniors, a product called Medicare Advantage. Competition is fierce for

Read More

Pizza-making robot startup Picnic raises $3M as pandemic puts spotlight on food automation

Picnic’s pizza-making robot at CES earlier this year. (GeekWire Photo / Taylor Soper)

Seattle startup Picnic raised an additional $3 million from existing investors as it gears up for a commercial rollout of its pizza-making robot.

Vulcan Capital, Flying Fish Partners, Creative Ventures, Arnold Venture Group, and others put more money behind Picnic, known for its automated food preparation device that can churn out up to 300 12-inch customized pizzas per hour. It follows a $5 million seed round in November.

The fresh cash will be used for product development, response to customer interest, new hires, and marketing. The company has seen increased demand for its machine during the pandemic from customers looking for ways to prepare food with less contact.

“This work is important because we’re supporting struggling restaurants who are looking for any advantage that will help them weather the storm of losing 60% of their sales,” CEO

Read More